Como away tickets on sale from 2 October; Roma face restrictions for 11 October fixture

Leonardo Balerdi is expected to start in defence for Roma's match against Inter, taking a place ahead of either Evan N'Dicka or Mario Hermoso. Wesley will operate on the left, while Matías Soulé and Paulo Dybala are set to play behind Donyell Malen in the forward line. A battle between Nahuel Molina and Emanuele Lulli remains unresolved ahead of the fixture. Gasperini said of the challenge: "Inter nettamente più forte, ma proveremo a inserirci. Massa? Sarà perfetto" (Inter are markedly stronger, but we will try to insert ourselves. Massa will be perfect). The match at the Olimpico is expected to draw over 60,000 supporters, with gates opening from 15:30.

Roma and Inter, the only two Serie A sides with 12 points after four rounds, meet at the Olimpico on Saturday in a high-stakes title clash. Gian Piero Gasperini's side have made a superb start to their second season in charge, winning all four league matches by an aggregate of 12–1, including a 2–0 victory at Torino on Monday with goals from Donyell Malen and Niccolò Pisilli. That came after a 1–1 draw at Fenerbahce in their opening Europa League fixture. Roma will attempt to reverse a damaging recent record: they have won only two of their last 16 encounters with Inter (D6, L10), and have lost their last five league clashes against them at home, failing to score four times in that sequence. The Giallorossi will seek to avenge an embarrassing 5–2 defeat from their last meeting. Despite the historical disadvantage, Roma's form this season suggests they can compete. They are the only Serie A team to have scored at least two goals in each of the first four rounds, and have extended their remarkable winning streak in the division to 11 games, including matches from last season. They are the second-highest scorers in Italy's top flight after four matchdays. Roma are also unbeaten in their last 14 home league matches (W11, D3) and boast one of the best defensive records in Europe's top-five leagues this season—only Arsenal and Freiburg have conceded as few goals as the Giallorossi (1). Inter, the reigning champions, are unbeaten in their last 30 Serie A games (W23, D6) despite netting just once in their only league trip so far in 2026–27, a narrow win over Cagliari. They top the scoring charts with 13 goals and have demonstrated remarkable fighting spirit, coming from 2–0 down to beat Napoli 3–2 and Udinese 5–3. However, they have conceded five goals across their last two league matches and let in at least two goals in three of their last five Serie A away games. Gasperini will have his entire squad available on Saturday, with Wesley Franca and Evan N'Dicka resuming full training earlier in the week. Manu Koné, who came off the bench at Turin, could return to the starting lineup in place of Pisilli. Paulo Dybala and Matías Soulé are expected to start behind Malen. Inter will be without midfielder Hakan Calhanoglu (adductor strain) and summer signing John Stones (thigh injury), with Yann Bisseck, Manuel Akanji and Alessandro Bastoni forming the defensive trio. Marcus Thuram could make his first Serie A start of the season after two impressive substitute appearances. Roma's projected lineup: Svilar; Mancini, Balerdi, N'Dicka; Molina, Koné, Cristante, Wesley; Soulé, Dybala; Malen. Inter's projected lineup: J. Martínez; Bisseck, Akanji, Bastoni; Diouf, Barella, Zielinski, Jones, Dimarco; Thuram, L. Martínez.

Daniele Aloisi has been appointed to referee the Roma-Inter match. The official's history against Roma is regarded as unfavourable, but head coach Gian Piero Gasperini has expressed confidence in him, saying he will be "perfect". Gasperini acknowledged Inter's superiority ahead of the fixture, stating: "Inter nettamente più forte, ma proveremo a inserirci" (Inter are considerably stronger, but we will try to get involved). The Roma manager framed the referee question as a non-issue, focusing instead on the tactical challenge posed by their opponents. On 18 September, Roma held their final training session before entering a retreat at Trigoria, part of Gasperini's preparation strategy for the match.